Targeting cyclic-AMP/phosphodiesterase signaling to quiet nasal tuft cell calcium responses
Kyle Polen, Li Eon Kuek, Zhongming Ma, Nithin D. Adappa, James N. Palmer, Ryan M. Carey, Robert J. Lee
This study investigates the role of cyclic-AMP/phosphodiesterase signaling in modulating nasal tuft cell calcium responses and IL-25 release using mouse and human models.
bioRxiv · Oct 25, 2026 · PreprintPhysiology