Author

Liang Lu

Dartmouth Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Pathology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:spatial domain detection· 2 Assay:spatial transcriptomics· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Adrienne A. WorkmaniD· 2 shared Xiaoying LiuiD· 2 shared Cassandra J Limoge· 1 shared Chenhong LiiD· 1 shared George J. ZanazziiD· 1 shared Jiantao HuiD· 1 shared Louis Joseph VaickusiD· 1 shared Mingwei Zhou· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersPathology

Adrienne A. WorkmanORCID

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3 papers

Recent·Most cited

Interpreting and Validating a Deep Learning Model Predictive of Spatial Morphologic-Molecular Patterns in Lung Adenocarcinoma, Using Ground Truth Immunohistochemistry

Vibha R Rao, Adrienne A. Workman, Scott M. Palisoul, Cassandra J Limoge, Louis Joseph Vaickus, George J. Zanazzi, Liang Lu, Xiaoying Liu, Shrey Sukhadia

XpressO-Lung predicts spatial gene expression patterns in lung adenocarcinoma using histopathology images, validated against immunohistochemistry, showing strong concordance with known morphologic features.

bioRxiv · Apr 23, 2026 · PreprintPathology

Interpretable Deep Learning Reveals Biologically Relevant Spatial Gene Expression Patterns in Lung Tumors and their Microenvironment

Vibha R. Rao, Adrienne A. Workman, Liang Lu, Xiaoying Liu, Shrey S. Sukhadia

XpressO-Lung predicts spatial gene expression patterns in LUAD tumors and their microenvironment from H&E images, achieving high accuracy and aligning with known biological interactions.

bioRxiv · Sep 17, 2025 · PreprintPathology

Resolving Taxonomic Conflicts in Trichiurus: Chromosome Genomics Clarifies Species and Informs Conservation of Populations in the Northwest Pacific

Vanthu Giap, Tian Wu, Liang Lu, Jiantao Hu, Mingwei Zhou, Chenhong Li

This study resolves taxonomic conflicts in Trichiurus species using chromosome genomics, identifies a new species, and informs conservation strategies for Northwest Pacific populations.

bioRxiv · Mar 5, 2025 · PreprintEvolutionary Biology