Author

Adrienne A. Workman

Dartmouth CollegeORCID 0009-0007-5088-0690Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell-cell communication· 3 Approach:deep learning· 3 Research Focus:spatial domain detection· 3 Assay:spatial transcriptomics· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Shrey SukhadiaiD· 3 shared Xiaoying LiuiD· 3 shared George J. ZanazziiD· 2 shared Liang Lu· 2 shared Louis Joseph VaickusiD· 2 shared Scott M. Palisoul· 2 shared Candice C. BlackiD· 1 shared Cassandra J Limoge· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersPathology

Shrey SukhadiaORCID

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4 papers

Recent·Most cited

PathologybioRxivPreprintApr 23, 2026

Interpreting and Validating a Deep Learning Model Predictive of Spatial Morphologic-Molecular Patterns in Lung Adenocarcinoma, Using Ground Truth Immunohistochemistry

Vibha R Rao, Adrienne A. Workman, Scott M. Palisoul…·Shrey Sukhadia

XpressO-Lung predicts spatial gene expression patterns in lung adenocarcinoma using histopathology images, validated against immunohistochemistry, showing strong concordance with known morphologic features.

DOI 10.64898/2026.04.20.719723

humanbulk RNA-seq

𝕏 PostBluesky

PathologybioRxivPreprintFeb 11, 2026

X-SPATIO: An Explanatory Deep Learning Pipeline for the Prediction and Visualization of Spatially Resolved Biomarker Expression in Triple-Negative Breast Cancer

V. Madhusudhan Rao, Madhumala K. Sadanandappa, Candice C. Black…·Shrey Sukhadia

X-SPATIO predicts and visualizes spatially resolved biomarker expression in TNBC by linking H&E morphology with spatial transcriptomic and proteomic data.

2 citations

humanspatial transcriptomics

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PathologybioRxivPreprintSep 17, 2025

Interpretable Deep Learning Reveals Biologically Relevant Spatial Gene Expression Patterns in Lung Tumors and their Microenvironment

Vibha R. Rao, Adrienne A. Workman, Liang Lu…·Shrey S. Sukhadia

XpressO-Lung predicts spatial gene expression patterns in LUAD tumors and their microenvironment from H&E images, achieving high accuracy and aligning with known biological interactions.

DOI 10.1101/2025.09.17.674367

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsbioRxivPreprintApr 16, 2023

Predicting Distant Recurrences in Invasive Breast Carcinoma Patients Using Clinicopathological Data: A cross-institutional and AI-based study

Shrey Sukhadia, Kristen E. Muller, Adrienne A. Workman, Shivashankar Hiriyur Nagaraj

This study uses clinicopathological data and AI models to predict distant recurrences in invasive breast carcinoma patients, showing cross-institutional validity with AUC 0.75-1.0.

DOI 10.1101/2023.04.16.537076

humanmachine learning (classical)

𝕏 PostBluesky