DNAH3 deficiency causes flagellar inner dynein arm loss and male infertility in humans and mice
Xiang Wang, Gan Shen, Yihong Yang, Chuan Jiang, Tiechao Ruan, Xue Yang, Liangchai Zhuo, Yingteng Zhang, Yangdi Ou, Xinya Zhao, Shunhua Long, Xiangrong Tang, Tingting Lin, Ying Shen
This study identifies DNAH3 variants in infertile men and shows that DNAH3 deficiency causes flagellar inner dynein arm loss and male infertility in humans and mice.
eLife · Nov 6, 2024Peer-reviewedGenetics