Author

Lilia Kaustov

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Biophysics· 1

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Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:statistical model· 1

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Abdellah Allali-Hassani· 1 shared Alexander Lemak· 1 shared Cheryl H. ArrowsmithiD· 1 shared Hong Wu· 1 shared Hong ZengiD· 1 shared Lixin Fan· 1 shared Marco Faini· 1 shared Masoud VedadiiD· 1 shared

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Abdellah Allali-Hassani

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintApr 26, 2018

MLL1 minimal catalytic complex is a dynamic conformational ensemble susceptible to pharmacological allosteric disruption

Lilia Kaustov, Alexander Lemak, Hong Wu…·Cheryl H. Arrowsmith

The paper investigates the dynamic structure of the MLL1 catalytic complex and shows it can be disrupted by pharmacological agents targeting specific interaction sites.

DOI 10.1101/308676

ChIP-seqexperimental assay

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