Author

Lixin Fan

Primary ORCID profile (0000-0002-9232-9262 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Lixin FaniD3 papers · Frederick National Laboratory for Cancer Research

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Abdellah Allali-Hassani· 1 shared Alexander Lemak· 1 shared Bin DuaniD· 1 shared Chen TangiD· 1 shared Chenyu ZhuiD· 1 shared Cheryl H. ArrowsmithiD· 1 shared Hong Wu· 1 shared Hong ZengiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

Abdellah Allali-Hassani

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2 papers

Recent·Most cited

Privacy-preserving integration of multiple institutional data for single-cell type identification with scPrivacy

Shaoqi Chen, Bin Duan, Chenyu Zhu, Chen Tang, Shuguang Wang, Yicheng Gao, Shaliu Fu, Lixin Fan, Qiang Yang, Qi Liu

scPrivacy enables privacy-preserving integration of single-cell RNA-seq datasets from multiple institutions for cell type identification.

Science China Life Sciences · Dec 15, 2022Peer-reviewedBioinformatics

MLL1 minimal catalytic complex is a dynamic conformational ensemble susceptible to pharmacological allosteric disruption

Lilia Kaustov, Alexander Lemak, Hong Wu, Marco Faini, Scott Houliston, Lixin Fan, Xianyang Fang, Hong Zeng, Shili Duan, Abdellah Allali-Hassani, Masoud Vedadi, Ruedi Aebersold, Yunxing Wang, Cheryl H. Arrowsmith

The paper investigates the dynamic structure of the MLL1 catalytic complex and shows it can be disrupted by pharmacological agents targeting specific interaction sites.

bioRxiv · Apr 26, 2018 · PreprintBiophysics