Author

Lillian M. Khan

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:metagenomics· 4 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 2 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Joseph L. DeRisiiD· 4 shared Charles LangelieriD· 3 shared Michael R. WilsoniD· 3 shared Akshaya RameshiD· 2 shared Emily D. CrawfordiD· 2 shared Eric D. ChowiD· 2 shared Katrina KalantariD· 2 shared Madeline Y. MaydayiD· 2 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersGenomics

Joseph L. DeRisiORCID

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Author profile →

4 papers

Recent·Most cited

Unbiased metagenomic sequencing for pediatric meningitis in Bangladesh reveals neuroinvasive Chikungunya virus outbreak and other unrealized pathogens

Senjuti Saha, Akshaya Ramesh, Katrina Kalantar, Roly Malaker, Md Hasanuzzaman, Lillian M. Khan, Madeline Y. Mayday, Mohammad Saiful Islam Sajib, Lucy M. Li, Charles Langelier, Hafizur Rahman, Emily D. Crawford, Cristina M. Tato, Maksuda Islam, Yun-Fang Juan, , Joseph L. DeRisi

This study uses metagenomic sequencing to identify pathogens in pediatric meningitis cases in Bangladesh, revealing a Chikungunya virus outbreak and other previously undetected causes.

mBio · Dec 16, 2019Peer-reviewedGenomics

Miniaturization and optimization of 384-well compatible metagenomic sequencing library preparation

Madeline Y. Mayday, Lillian M. Khan, Eric D. Chow, Matt S. Zinter, Joseph L. DeRisi

This paper describes a miniaturized and automated method for metagenomic sequencing library preparation that reduces costs and time while maintaining quality.

PLoS ONE · Jan 10, 2019Peer-reviewedMolecular Biology

Integrating Host Response and Unbiased Microbe Detection for Lower Respiratory Tract Infection Diagnosis in Critically Ill Adults

Charles Langelier, Katrina Kalantar, Farzad Moazed, Michael R. Wilson, Emily D. Crawford, Thomas J. Deiss, Annika Belzer, Samaneh Bolourchi, Saharai Caldera, Monica Fung, Alejandra Jauregui, Katherine B. Malcolm, Amy Lyden, Lillian M. Khan, Kathryn Vessel, , Joseph L. DeRisi

This paper develops a metagenomic sequencing approach to diagnose lower respiratory tract infections by integrating pathogen detection, microbiome analysis, and host transcriptome data.

Proceedings of the National Academy of Sciences · Nov 27, 2018Peer-reviewedGenomics

Pediatric Brainstem Encephalitis Outbreak Investigation with Metagenomic Next-Generation Sequencing

Kristoffer E. Leon, Didac Casas-Alba, Akshaya Ramesh, Lillian M. Khan, Cristian Launes, Hannah A. Sample, Kelsey C. Zorn, Ana Valero-Rello, Charles Langelier, Carmen Muñoz-Almagro, Joseph L. DeRisi, Michael R. Wilson

The paper investigates a pediatric brainstem encephalitis outbreak using metagenomic next-generation sequencing, finding that mNGS significantly improves EV-A71 detection in CSF and confirms the outbreak strain's relation to a neuroinvasive isolate.

bioRxiv · Sep 12, 2018 · PreprintMicrobiology