Akshaya Ramesh

Paired CSF and blood scRNA/TCR-seq in treatment-naive MS shows a small set of expanded, cytotoxic CSF-enriched CD8+ clonotypes, two of which recognize EBV epitopes.

This study uses metagenomic sequencing to identify pathogens in pediatric meningitis cases in Bangladesh, revealing a Chikungunya virus outbreak and other previously undetected causes.

The paper investigates a pediatric brainstem encephalitis outbreak using metagenomic next-generation sequencing, finding that mNGS significantly improves EV-A71 detection in CSF and confirms the outbreak strain's relation to a neuroinvasive isolate.

This study uses metagenomic sequencing and the IDseq platform to identify microbial pathogens in Ugandan children with fever, revealing common pathogens and novel viruses.