Genomic and Epigenetic Interplay Drives Adaptive Fusion via Reproduction Trade-Off
Yang Chen, Lin Bi, Xiaoli Fan, Shuang Liang, Chengyuan Li, Yihong Wang, Sophie G. Martin, Gaowen Liu
The paper shows how epigenetic silencing and genetic changes enable Prm1-independent fusion in yeast, but at the cost of mitotic growth, while synthetic mutations avoid this trade-off.
bioRxiv · Sep 26, 2025 · PreprintEvolutionary Biology