Author

Linda van der Graaf

Leiden University Medical Center

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Genetics· 1

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Barry A. PepersiD· 1 shared Davy CatsiD· 1 shared Eleni MinaiD· 1 shared Elsa C. KuijperiD· 1 shared Hailiang MeiiD· 1 shared Lodewijk J.A. TooneniD· 1 shared Mariana Guimarães RamosiD· 1 shared Ronald A.M. BuijseniD· 1 shared

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2025-2025 · peak 1/yr

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Barry A. PepersORCID

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1 paper

Recent·Most cited

GeneticsHuman Molecular GeneticsPeer-reviewedSep 23, 2025

Determining off-target effects of splice-switching antisense oligonucleotides using short read RNAseq in neuronally differentiated human induced pluripotent stem cells

Elsa C. Kuijper, Linda van der Graaf, Barry A. Pepers…·Willeke van Roon‐Mom

This study uses RNAseq to assess off-target effects of three splice-switching AONs in human cells, identifying splicing changes and showing variability in AON-induced effects.

5 citations

humanbulk RNA-seq

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