Davy Cats

The paper evaluates the therapeutic effects of hiMSCs in osteoarthritis models, showing reduced damage and activation of cholesterol pathways, with spatial transcriptomics revealing localized molecular changes.

This paper introduces lncRNA-BERT, an RNA language model that classifies coding and long non-coding RNAs, outperforming existing methods on benchmark datasets.

This study uses RNAseq to assess off-target effects of three splice-switching AONs in human cells, identifying splicing changes and showing variability in AON-induced effects.

This study identifies biallelic germline variants in MCM8 and MCM9 as linked to polyposis, gastric cancer, early-onset colorectal cancer, and hypogonadism, with MCM9 variants showing stronger associations.

The paper constructs a transcriptome atlas of human leg muscles, identifying molecular and cellular differences associated with muscle location and function.

The paper identifies differentially expressed lncRNAs in OA cartilage and validates their regulatory role on adjacent genes.

The paper benchmarks 20 automatic cell identification methods for single-cell RNA-sequencing data across eight datasets, finding that SVM performs best overall.