Systematic toxicological study of PFOS/PFOA co-exposure driving prostate cancer: Core target identification, TME immune remodeling, and combination drug prediction
Jiawei Pan, Yuan Zhang, Anqi Yang, Linglong JIANG, Yuwei SHEN, Yangyang SUN, Jundong ZHU, Min FAN, Jian SHI
This paper identifies core targets and mechanisms of PFOS/PFOA-induced prostate cancer and predicts combination drug therapy using computational methods.
bioRxiv · May 12, 2026 · PreprintPharmacology & Toxicology