Author

Yuan Zhang

Fudan UniversityORCID 0000-0001-5538-1478Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yuan Zhang7 papers · University of Electronic Science and Technology of China

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Anqi YangiD· 1 shared Behnam JavidfariD· 1 shared Bibi S. Kassim· 1 shared Bluma J. LeschiD· 1 shared Cyril Jayakumar PeteriD· 1 shared Daijing SuniD· 1 shared Esperanza Agulló-PascualiD· 1 shared Haixin LiiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

Anqi YangORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintMay 12, 2026

Systematic toxicological study of PFOS/PFOA co-exposure driving prostate cancer: Core target identification, TME immune remodeling, and combination drug prediction

Jiawei Pan, Yuan Zhang, Anqi Yang…·Jian SHI

This paper identifies core targets and mechanisms of PFOS/PFOA-induced prostate cancer and predicts combination drug therapy using computational methods.

DOI 10.64898/2026.05.07.723528

humanbulk RNA-seq

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NeuroscienceNature CommunicationsPeer-reviewedDec 13, 2021

NEURON-SPECIFIC CHROMOSOMAL MEGADOMAIN ORGANIZATION IS ADAPTIVE TO RECENT RETROTRANSPOSON EXPANSIONS

Sandhya Chandrasekaran, Sergio Espeso‐Gil, Yong‐Hwee Eddie Loh…·Schahram Akbarian

The paper shows that neuron-specific chromatin domains in mice are shaped by recent retrotransposon expansions and that disrupting a silencer leads to chromatin rewiring and neuroinflammation.

26 citations

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