Muskelin acts as a substrate receptor of the highly regulated Drosophila CTLH E3 ligase during the maternal-to-zygotic transition
Chloe A. Briney, Jesslyn C. Henriksen, Chenwei Lin, Lisa A. Jones, Leif Benner, Addison B. Rains, Roxana Gutierrez, Philip R. Gafken, Olivia S. Rissland
The paper identifies Muskelin as a substrate adaptor for the Drosophila CTLH E3 ligase, showing how it regulates the degradation of RNA-binding proteins during the maternal-to-zygotic transition.
bioRxiv · Jun 28, 2024 · PreprintDevelopmental Biology