Urothelial-lineage master transcription factor hub proteomics shows mechanisms impeding urothelial cancer cell differentiation
Caroline Schuerger, Sudipta Biswas, Kwok Peng Ng, Lisa Cardone, Xiaorong Gu, Shinjini Ganguly, Rita Tohmé, Arda Durmaz, Maximilian Stich, Daniel J. Lindner, Babal Kant Jha, Omar Y. Mian, Yogen Saunthararajah
The paper identifies CoA and CoR dysregulation in urothelial cancer cells and shows that CoR inhibition can restore differentiation.
bioRxiv · Aug 17, 2026 · PreprintCancer Biology