Activated macrophages restrict invasive bacterial infection in a human intestinal organoid co-culture model
Lisa Goertz, Marcella Cipelli, Manuela Büettner, Guntram A. Graßl, Matthias Lochner
The paper develops a human intestinal organoid co-culture model with macrophages to study bacterial infection control, finding that activated macrophages reduce bacterial burden and cytotoxicity.
bioRxiv · Sep 10, 2026 · PreprintImmunology