Contribution of front-line, standard of care drugs to bactericidal responses, resistance emergence, and cure in murine models of easy- or hard-to-treat tuberculosis disease
Nathan Peroutka‐Bigus, Elizabeth J. Brooks, Michelle E. Ramey, Hope D’Erasmo, Jacqueline P. Ernest, Allison Bauman, Lisa K. Woolhiser, Radojka M. Savić, Anne J. M. Lenaerts, Bree B. Aldridge, Jansy Passiflora Sarathy, Gregory T. Robertson
The paper evaluates the effectiveness of standard TB drugs in mice, showing rifampin's critical role in killing bacteria and preventing resistance.
Antimicrobial Agents and Chemotherapy · Mar 26, 2025Peer-reviewedMicrobiology