Lisa Morrison Baird

The Mutational Dynamics of Short Tandem Repeats in Large, Multigenerational Families

The paper estimates the genome-wide de novo STR mutation rate in human pedigrees and identifies factors influencing STR mutation dynamics.

De novo structural mutation rates and gamete-of-origin biases revealed through genome sequencing of 2,396 families

The paper reports de novo structural mutation rates and gamete-of-origin biases using genome sequencing of 2,396 families, finding higher rates in autism cases and paternal origin dominance.

Pedigree-based estimation of human mobile element retrotransposition rates

The paper estimates human retrotransposition rates for L1, Alu, and SVA elements using WGS data from 33 three-generation pedigrees, finding rates and parent-of-origin effects.

Large, three-generation CEPH families reveal post-zygotic mosaicism and variability in germline mutation accumulation

The paper analyzes de novo mutations in three-generation CEPH families to show variability in mutation rates and identifies post-zygotic mosaicism as a source of de novo mutations.

Instability in 18S and 5.8S rDNA copy numbers and 18S:5.8S ratios in longitudinally-collected human DNA samples detected by monochrome multiplex qPCR

This study uses qPCR to detect longitudinal changes in 18S and 5.8S rDNA copy numbers and their ratio in human DNA samples over 16 years.