Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke C. Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez
This paper demonstrates that the RALA peptide effectively delivers CRISPR components in DNA, RNA, and RNP formats to primary mesenchymal stem cells with high viability and low cytotoxicity.
Advanced Functional Materials · Sep 2, 2025Peer-reviewedBioengineering