Author

Lisette Ruuls

Wageningen University & Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Organism:non-human primate· 1 Organism:plant (other)· 1

Frequent Co-Authors

Ignacio CaballeroiD· 2 shared Jean‐Claude SirardiD· 2 shared Mara BaldryiD· 2 shared Norbert Stockhofe-ZurwiedeniD· 2 shared Alain Deslis· 1 shared Alexis Pléau· 1 shared Arndt BeneckeiD· 1 shared Céline BarciD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Ignacio CaballeroORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Flagellin nebulization enhances respiratory immune responses in the porcine model

Mara Baldry, Ignacio Caballero, Lisette Ruuls, Delphine Cayet, Yasmine Zeroual, Charlotte Costa, Delphine Beury, David Hot, Yves Le Vern, Nathalie Heuzé‐Vourc'h, Ronan J. MacLoughlin, Arndt Benecke, Norbert Stockhofe-Zurwieden, Jean‐Claude Sirard

This study shows that nebulized FLAMOD, a flagellin agonist, induces a robust immune response in pigs without adverse effects, highlighting innate immunity and bacterial defense pathways.

iScience · Nov 25, 2025Peer-reviewedImmunology

Flagellin aerosol administration improves the efficacy of antibiotic treatment in Actinobacillus pleuropneumoniae infected pigs

Isabelle Fleurot, Vanaïque Guillory, Céline Barc, Mickaël Riou, Alain Deslis, Alexis Pléau, Thibaut Larcher, Mara Baldry, Sascha Trapp, Norbert Stockhofe-Zurwieden, Lisette Ruuls, Conny B. van Solt-Smits, Jean‐Claude Sirard, Ignacio Caballero

This study shows that combining aerosolized FLAMOD with subtherapeutic penicillin G improves bacterial clearance and reduces lung lesions in pigs infected with Actinobacillus pleuropneumoniae.

bioRxiv · Mar 17, 2025 · PreprintImmunology