Single cell proteomics characterization of bone marrow hematopoiesis with distinct Ras pathway lesions.
Laila Karra, Anna‐Marie Finger, Lauren A. Shechtman, Milana Krush, Mengyao Huang, Morgan Prinz, Iliana Tenvooren, Kriti Bahl, Lisiena Hysienaj, Paulina A García-González, Alexis J. Combes, Hugo González Velozo, Rafael José Argüello, Matthew H. Spitzer, Jeroen P. Roose
The paper uses single-cell proteomics and metabolomics to study how Ras pathway mutations affect hematopoiesis, finding distinct impacts on HSC compartments and metabolism.
Blood Advances · Jul 30, 2025Peer-reviewedDevelopmental Biology