Mice with impaired synaptic facilitation exhibit deficits in cognitive flexibility
Chloé L. Le Moing, Anna M. Bowman, Milana Krush, Joseph Gordon, Aaliya Mehnaz Ahmed, Skyler L. Jackman
This study shows that mice lacking Synaptotagmin-7, which is required for synaptic facilitation, have impaired cognitive flexibility in dynamic reward tasks but not in stable ones.
bioRxiv · Aug 12, 2026 · PreprintNeuroscience