BioengineeringbioRxivPreprint
Relief of allosteric inhibition, redox imbalance, and transport limitations enables high-yield L-malate production in Escherichia coli
Moses Onyeabor, Lizbeth M. Nieves, Gavin Kurgan…·Xuan Wang
This study improves an Escherichia coli strain for high-yield L-malate production by modifying allosteric regulation, redox balance, and transport, achieving a mass yield of 1.2 g malate per gram of glucose.