Local demyelination rekindles oligodendrocyte precursor dynamics and remyelination in old age
Katharina Eichenseer, Shahrzad Askari, Llazar Shkurti, Thomas Misgeld, Nicolas Snaidero
This study shows that OPCs in aging retain remyelination potential, which can be reactivated by demyelination, improving myelin repair.
bioRxiv · Feb 16, 2026 · PreprintNeuroscience