Effects of NAD⁺ Repletion with Nicotinamide Riboside on Obesity-Induced Chronic Kidney Disease and Renal Cell Lipotoxicity
Morgane Decarnoncle, Louise Pierre, Marine Thirion, Hélène Marlier, Louis Maréchal, Pauline Rouzé, Inès Jadot, Thierry Arnould, Anne‐Émilie Declèves, Florian Juszczak
This study investigates the effects of nicotinamide riboside (NR) on obesity-induced chronic kidney disease and renal cell lipotoxicity in mice, finding antioxidant and mitochondrial benefits in vitro but no metabolic protection in vivo.
Scientific Reports · Apr 9, 2026Peer-reviewedBiochemistry