Thierry Arnould

This study investigates the effects of nicotinamide riboside (NR) on obesity-induced chronic kidney disease and renal cell lipotoxicity in mice, finding antioxidant and mitochondrial benefits in vitro but no metabolic protection in vivo.

The paper investigates how mitochondrial DNA variants affect telomere length using transmitochondrial cybrids, finding an inverse correlation between donor telomere length and mitochondrial ROS levels.

This study identifies MPV17 as a regulator of mitochondrial calcium and oxidative stress, showing its role in preventing mtDNA degradation through interactions with the MICOS complex.

This study shows that heme synthesis and succinate regulate pluripotent state transitions in ESCs by affecting signaling pathways and triggering 2C-like reprogramming.