Author

Lucas G. F. Couwenberg

Delft University of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Assay:DNA methylation· 1 Research Focus:genome assembly· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Arthur R. Gorter de VriesiD· 1 shared Eline D. Postma· 1 shared Jack T. PronkiD· 1 shared Jean-Marc G DaraniD· 1 shared Jolanda ter HorstiD· 1 shared Jordi Geelhoed· 1 shared Marcel A. van den BroekiD· 1 shared Pascale A. S. Daran-LapujadeiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Arthur R. Gorter de VriesORCID

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2 papers

Recent·Most cited

GeneticsmBioPeer-reviewedSep 21, 2022

Top-down, knowledge-based genetic reduction of yeast central carbon metabolism

Eline D. Postma, Lucas G. F. Couwenberg, Roderick N. van Roosmalen…·Pascale A. S. Daran-Lapujade

The paper reduces genetic complexity in yeast central carbon metabolism by deleting 35 genes, resulting in minimal phenotypic changes under various conditions.

8 citations

yeastexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintAug 22, 2018

Allele-specific genome editing using CRISPR-Cas9 causes off-target mutations in diploid yeast

Arthur R. Gorter de Vries, Lucas G. F. Couwenberg, Marcel A. van den Broek…·Jean-Marc G Daran

This study shows that CRISPR-Cas9 editing in diploid yeast causes off-target mutations and loss of heterozygosity due to homology-directed repair.

3 citations

yeastDNA methylation

𝕏 PostBluesky