Author

Lucas J Deden-Binder

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:dimensionality reduction· 1 Approach:machine learning (classical)· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Bruce R. FischliD· 2 shared Rogeny Herisse· 2 shared Yaël BalbastreiD· 2 shared Abigail Visser· 1 shared Achraf Malki· 1 shared Adam Willis· 1 shared Adrià CasamitjanaiD· 1 shared Adrian Vasile DalcaiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBioengineering

Bruce R. FischlORCID

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Author profile →

2 papers

Recent·Most cited

VesSynth: Tubes Are All You Need for Robust Cross-Scale Cross-Modal 3D Vessel Segmentation

Chiara Mauri, Allison McKenzie, Cole Analoro, Emma Yeon, Rose Coviello, Jocelyn Mora, Etienne Chollet, Lucas J Deden-Binder, Ara Mahar, Stephanie Lin, Malak Benlahcen, Angelina Ream, Aliyah Jama, Itzel Garcia, Nam Tran, , Yaël Balbastre

This paper introduces VesSynth, a vessel segmentation framework trained on synthetic data that achieves state-of-the-art accuracy across multiple imaging modalities and spatial resolutions.

bioRxiv · Apr 6, 2026 · PreprintBioengineering

Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology

Harshvardhan Gazula, Henry F. J. Tregidgo, Benjamin Billot, Yaël Balbastre, Jonathan Williams-Ramirez, Rogeny Herisse, Lucas J Deden-Binder, Adrià Casamitjana, Erica J. Melief, Caitlin S. Latimer, Mitchell D. Kilgore, Mark Montine, Eleanor Robinson, Emily Blackburn, Michael S Marshall, , Juan Eugenio Iglesias

The paper develops open-source tools for 3D analysis of brain dissection photographs and surface scans, achieving accurate reconstructions and segmentations comparable to MRI.

eLife · Dec 12, 2023Peer-reviewedNeuroscience