Author

Lucas R. Brenes

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Microbiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alexander D. JohnsoniD· 2 shared Naomi ZiviD· 2 shared Alexandra N. Borden· 1 shared Brendan T. FraineyiD· 1 shared Carl B W Soderstrom· 1 shared Charles S. CraikiD· 1 shared Douglass B. ClaytoniD· 1 shared Elise Turner· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersSystems Biology

Alexander D. JohnsonORCID

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Author profile →

3 papers

Recent·Most cited

Unmasking Pathogen Traits for Chronic Colonization in Neurogenic Bladder Patients

Seth A. Reasoner, Brendan T. Frainey, Owen F. Hale, Alexandra N. Borden, M. Kyle Graham, Elise Turner, Lucas R. Brenes, Carl B W Soderstrom, Hamilton Green, Jonathan E. Schmitz, Michael T. Laub, Maryellen S. Kelly, Douglass B. Clayton, Maria Hadjifrangiskou

The paper studies microbial colonization in neurogenic bladder patients, identifying patterns of bacterial persistence and mutations linked to immune evasion and phage resistance.

Cell Reports · Apr 22, 2026Peer-reviewedMicrobiology

Multiple molecular events underlie stochastic switching between two heritable cell states in a eukaryotic system

Naomi Ziv, Lucas R. Brenes, Alexander D. Johnson

The paper investigates stochastic switching between two heritable cell states in Candida albicans using microfluidics and fluorescent reporters, identifying two stochastic steps involving Wor1 autoregulation.

bioRxiv · Sep 23, 2021 · PreprintSystems Biology

An opaque cell-specific expression program of secreted proteases and transporters allows cell-type cooperation in Candida albicans

Matthew B. Lohse, Lucas R. Brenes, Naomi Ziv, Michael B. Winter, Charles S. Craik, Alexander D. Johnson

The paper shows that opaque cells in C. albicans up-regulate proteases and transporters to efficiently use proteins as nitrogen sources, enabling white cells to proliferate in mixed cultures.

Genetics · Aug 24, 2020Peer-reviewedGenetics