Author

Lucie Lafleur

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Aurélien FouilleniD· 1 shared Bernard MouillaciD· 1 shared Charline MaryiD· 1 shared Christiane MendreiD· 1 shared Gunnar SchulteiD· 1 shared Hélène OrceliD· 1 shared Julien BousiD· 1 shared Nicolas GillesiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperPharmacology & Toxicology

Aurélien FouillenORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Inactive structures of the vasopressin V2 receptor reveal distinct antagonist binding modes for Tolvaptan and Mambaquaretin toxin

Aurélien Fouillen, Julien Bous, Pierre Couvineau, Hélène Orcel, Charline Mary, Lucie Lafleur, Timothé Pierre, Christiane Mendre, Nicolas Gilles, Gunnar Schulte, Sébastien Granier, Bernard Mouillac

The paper solves cryo-EM structures of the V2R bound to Tolvaptan and Mambaquaretin toxin, revealing distinct antagonist binding modes and inactive conformations.

Nature Communications · Apr 24, 2025Peer-reviewedPharmacology & Toxicology