Author

Bernard Mouillac

Centre National de la Recherche ScientifiqueORCID 0000-0002-3906-8673Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Aurélien FouilleniD· 1 shared Charline MaryiD· 1 shared Christiane MendreiD· 1 shared Gunnar SchulteiD· 1 shared Hélène OrceliD· 1 shared Julien BousiD· 1 shared Lucie Lafleur· 1 shared Nicolas GillesiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Aurélien FouillenORCID

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1 paper

Recent·Most cited

Inactive structures of the vasopressin V2 receptor reveal distinct antagonist binding modes for Tolvaptan and Mambaquaretin toxin

Aurélien Fouillen, Julien Bous, Pierre Couvineau, Hélène Orcel, Charline Mary, Lucie Lafleur, Timothé Pierre, Christiane Mendre, Nicolas Gilles, Gunnar Schulte, Sébastien Granier, Bernard Mouillac

The paper solves cryo-EM structures of the V2R bound to Tolvaptan and Mambaquaretin toxin, revealing distinct antagonist binding modes and inactive conformations.

Nature Communications · Apr 24, 2025Peer-reviewedPharmacology & Toxicology