PAK3 controls the tangential to radial migration switch of cortical interneurons by coordinating changes in cell shape and polarity
Lucie Viou, Pierre Launay, Véronique Rousseau, Justine Masson, Clarisse Pace, Robert S. Adelstein, X. Ma, Zhengping Jia, Fujio Murakami, Jean‐Vianney Barnier, Christine Métin
This study shows that PAK3 kinase activity regulates the switch from tangential to radial migration in cortical interneurons by affecting cell shape and polarity.
bioRxiv · Jul 6, 2020 · PreprintDevelopmental Biology