Christine Métin

This study shows that KIF7 deletion in mice disrupts cerebral cortex development by altering SHH signaling differently in dorsal and ventral forebrain regions, leading to structural and migratory defects in neurons.

The paper shows that CXCL12 modulates the ciliary cAMP/cGMP ratio to control cell polarity and directed migration in cortical interneurons.

The paper shows that primary cilia regulate neuronal migration through cAMP/PKA signaling at the centrosome, with genetic and imaging experiments demonstrating the role of ciliary Adenylate Cyclase 3 and centrosomal PKA.

This study shows that PAK3 kinase activity regulates the switch from tangential to radial migration in cortical interneurons by affecting cell shape and polarity.