The ciliary kinesin KIF7 controls the development of the cerebral cortex by acting differentially on SHH-signaling in dorsal and ventral forebrain
María Pedraza, Valentina Grampa, Sophie Scotto‐Lomassese, Julien Puech, Aude Muzerelle, Azka Mohammad, Sophie Lebon, Nicolas Renier, Christine Métin, Justine Masson
This study shows that KIF7 deletion in mice disrupts cerebral cortex development by altering SHH signaling differently in dorsal and ventral forebrain regions, leading to structural and migratory defects in neurons.
bioRxiv · Mar 21, 2024Neuroscience