Predicting hypersensitivity and comorbid depressive-like behavior in late stages of joint disease using early weight bearing deficit
Sara Hestehave, Roxana Florea, Alex J. H. Fedorec, Maria Jevic, Lucile Mercy, Annia Wright, Oakley B. Morgan, Laurence A. Brown, Stuart N. Peirson, Sandrine M. Géranton
The paper shows that early functional measures in joint disease models predict long-term sensory and emotional symptoms, suggesting their use in clinical settings for better pain management and prevention of emotional comorbidities.
bioRxiv · Nov 29, 2023 · PreprintNeuroscience