Author

Lucy Sykes

Novo Nordisk (India)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrian Baez‐OrtegaiD· 1 shared Alex Byrne· 1 shared Amy L. RobertsiD· 1 shared Andrew R. J. LawsoniD· 1 shared Anna L. MooniD· 1 shared Anna PatersoniD· 1 shared Ayrun NessaiD· 1 shared Belma Jakupovic· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetic & Genomic Medicine

Adrian Baez‐OrtegaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Somatic mutation and selection at epidemiological scale

Andrew R. J. Lawson, Federico Abascal, Pantelis A. Nicola, Stefanie V. Lensing, Amy L. Roberts, Georgios Kalantzis, Adrian Baez‐Ortega, Natalia Brzozowska, Julia S. El-Sayed Moustafa, Dovile Vaitkute, Belma Jakupovic, Ayrun Nessa, Samuel Wadge, Anna Paterson, Doris M. Rassl, , Iñigo Martincorena

The paper introduces a high-accuracy sequencing method to detect somatic mutations in tissues, revealing extensive selection and driver mutations in oral epithelium and blood samples.

medRxiv · Oct 30, 2024 · PreprintGenetic & Genomic Medicine

Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by mutation of the psychiatric risk gene Cacna1c

Cezar M. Tigaret, Tzu‐Ching E. Lin, Edward Morrell, Lucy Sykes, Anna L. Moon, Michael C. O’Donovan, Michael John Owen, Lawrence S. Wilkinson, Matthew W. Jones, Kerrie L. Thomas, Jérémy Hall

The paper shows that activating neurotrophin receptors with BDNF mimetics can rescue cognitive and synaptic deficits caused by Cacna1c mutations in rats.

Molecular Psychiatry · Feb 17, 2021Peer-reviewedNeuroscience