Mutations in Drosophila tRNA processing factors cause phenotypes similar to Pontocerebellar Hypoplasia
Casey A. Schmidt, Lucy Y. Min, Michelle H. McVay, Joseph D. Giusto, John C. Brown, Harmony R. Salzler, A. Gregory Matera
This study shows that mutations in Drosophila tRNA processing factors cause phenotypes similar to human Pontocerebellar Hypoplasia, including reduced brain size and motor dysfunction.
Biology Open · Feb 8, 2022Peer-reviewedGenetics