eIF5A is an indispensable protein for eukaryotic cells
Samoa Prieto-Diez, Alejandro Aguilar-Díaz, Luis Araque, David Peris, Paula M. Alepuz
The paper identifies eIF5A as an indispensable protein in eukaryotic cells, showing that its duplicated paralogous genes act as a backup system to rescue mutations in the essential copy.
bioRxiv · Jul 23, 2026 · PreprintGenetics