Cytokine mRNA Delivery and Local Immunomodulation in the Placenta using Lipid Nanoparticles
Samuel I. Hofbauer, Luisa A. Fink, Rachel E. Young, Tara Vijayakumar, Katherine M. Nelson, Nia Bellopede, Mohamad‐Gabriel Alameh, Drew Weissman, Jason P. Gleghorn, Rachel Riley
This study uses lipid nanoparticles to deliver cytokine mRNA to placental cells, inducing anti-inflammatory responses and revealing dose-dependent polarization of macrophages.
Advanced Therapeutics · Jul 16, 2025Peer-reviewedBioengineering