Author

Rachel Riley

Rowan UniversityORCID 0000-0002-3267-5403Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Drew WeissmaniD· 2 shared Mohamad‐Gabriel AlamehiD· 2 shared Rachel E. YoungiD· 2 shared Samuel I. Hofbauer· 2 shared Tara VijayakumariD· 2 shared Diya Patel· 1 shared James M. HolaskaiD· 1 shared Jason P. GleghorniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersBioengineering

Drew WeissmanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Investigating the Impact of Hypoxia and Syncytialization on Lipid Nanoparticle-Mediated mRNA Delivery to Placental Cells

Rachel E. Young, Tara Vijayakumar, Logan J. Reilley, Krisha Darji, Diya Patel, Samuel I. Hofbauer, Mohamad‐Gabriel Alameh, Drew Weissman, Rachel Riley

This study evaluates how hypoxia affects lipid nanoparticle-mediated mRNA delivery to placental cells and shows that therapeutic mRNA can restore protein levels under hypoxic conditions.

Bioengineering & Translational Medicine · Jan 22, 2026Peer-reviewedBioengineering

Development of Emerin mRNA Lipid Nanoparticles to Rescue Myogenic Differentiation

Nicholas Marano, Liza Elif Guner, Rachel Riley, James M. Holaska

This study develops emerin mRNA lipid nanoparticles (EMD-LNPs) to restore emerin protein expression in emerin-null myogenic progenitors, improving differentiation and showing low toxicity.

International Journal of Molecular Sciences · Aug 12, 2025Peer-reviewedCell Biology

Cytokine mRNA Delivery and Local Immunomodulation in the Placenta using Lipid Nanoparticles

Samuel I. Hofbauer, Luisa A. Fink, Rachel E. Young, Tara Vijayakumar, Katherine M. Nelson, Nia Bellopede, Mohamad‐Gabriel Alameh, Drew Weissman, Jason P. Gleghorn, Rachel Riley

This study uses lipid nanoparticles to deliver cytokine mRNA to placental cells, inducing anti-inflammatory responses and revealing dose-dependent polarization of macrophages.

Advanced Therapeutics · Jul 16, 2025Peer-reviewedBioengineering