ImmunologyCell Death DiscoveryPeer-reviewed
SARS-CoV-2 and its ORF3a, E and M viroporins activate inflammasome in human macrophages and induce of IL-1α in pulmonary epithelial and endothelial cells
Magdalena Ambrożek-Latecka, Piotr Kozłowski, Grażyna Hoser…·Tomasz Skirecki
This study shows SARS-CoV-2 viroporins ORF3a, E, and M activate inflammasomes in macrophages and induce IL-1α release in pulmonary epithelial and endothelial cells, contributing to immunothrombosis in COVID-19.
24 citations