Characterizing the metabolomes of microglia, astrocytes, and neurons in aging and Alzheimer's brains
Jie Yu, Fengzhi Li, Xingjun Chen, Chenye Mou, Di Yao, Zhanying Bi, X. -Y. Chen, Lulu Du, Ziyan Feng, Xinshuang Zhang, Xiaojuan Yu, Lauren G. Zacharias, Ralph J. DeBerardinis, Li Zhang, Zhen Li, , Woo‐Ping Ge
The paper characterizes the metabolomes of microglia, astrocytes, and neurons in aging and Alzheimer's brains, identifying cell-type-specific metabolic pathways and their changes with age and disease.
bioRxiv · Feb 6, 2026 · PreprintNeuroscience