Author

Ziyan Feng

Chinese Institute for Brain Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:metabolomics· 1 Organism:rat· 1

Frequent Co-Authors

Woo‐Ping GeiD· 4 shared Daosheng Ai· 3 shared Jun-Liszt LiiD· 3 shared Wenzhi SuniD· 3 shared Xing-jun CheniD· 3 shared Zhanying BiiD· 3 shared Benyan LuoiD· 2 shared Fengzhi LiiD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersNeuroscience

Woo‐Ping GeORCID

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4 papers

Recent·Most cited

Characterizing the metabolomes of microglia, astrocytes, and neurons in aging and Alzheimer's brains

Jie Yu, Fengzhi Li, Xingjun Chen, Chenye Mou, Di Yao, Zhanying Bi, X. -Y. Chen, Lulu Du, Ziyan Feng, Xinshuang Zhang, Xiaojuan Yu, Lauren G. Zacharias, Ralph J. DeBerardinis, Li Zhang, Zhen Li, , Woo‐Ping Ge

The paper characterizes the metabolomes of microglia, astrocytes, and neurons in aging and Alzheimer's brains, identifying cell-type-specific metabolic pathways and their changes with age and disease.

bioRxiv · Feb 6, 2026 · PreprintNeuroscience

rAAV-miniBEND: A targeted vector for brain endothelial cell gene delivery and cerebrovascular malformation modeling

Jun-Liszt Li, Zhanying Bi, Xing-jun Chen, Tianyue Ming, Baoshan Qiu, Fengzhi Li, Ziyan Feng, Daosheng Ai, Tingting Zhang, Jiayu Wang, Shuai Lin, Yiping Lu, Zhen Wang, Juan Huang, Fei Zhao, , Woo‐Ping Ge

The paper develops a rAAV vector, rAAV-miniBEND, for specific gene delivery to brain endothelial cells and models cerebrovascular malformations like CCM and AVM.

bioRxiv · Jun 10, 2025 · PreprintNeuroscience

The subcommissural organ regulates brain development via secreted peptides

Tingting Zhang, Daosheng Ai, Pingli Wei, Ying Xu, Zhanying Bi, Fengfei Ma, Fengzhi Li, Xing-jun Chen, Zhaohuan Zhang, Xiaoxiao Zou, Zongpei Guo, Yue Zhao, Jun-Liszt Li, Meng Ye, Ziyan Feng, , Woo‐Ping Ge

The paper identifies three genes highly expressed in the subcommissural organ (SCO) and shows their ablation causes brain developmental defects, with peptide reintroduction rescuing these defects.

Nature Neuroscience · May 13, 2024Peer-reviewedNeuroscience

ADAM10 mediates macroglial cell fate decisions in the developing brain

Yihui Wang, Yue Liang, Daosheng Ai, Jun-Liszt Li, Ziyan Feng, Zhibao Guo, Xing-jun Chen, Tingting Zhang, Xiaoxiao Zou, Junli Gao, Xiaofei Gao, Xiao-Ling Hu, Long‐Jun Wu, Wenzhi Sun, Suiqiang Zhu, , Woo‐Ping Ge

The paper shows ADAM10 regulates macroglial cell fate by promoting astrocyte generation and inhibiting oligodendrocyte production in developing brains.

bioRxiv · Feb 11, 2023 · PreprintNeuroscience