Author

Luyuan Nong

University of Amsterdam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:whole-genome sequencing· 3 Research Focus:drug response / drug discovery· 2 Organism:E. coli· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Benno H. ter KuileiD· 3 shared Martijs J. JonkeriD· 3 shared Wim C. de LeeuwiD· 3 shared Xinyu Wang· 2 shared Belinda B. Koenders· 1 shared Gioia Schaar· 1 shared Meike T. WorteliD· 1 shared Stanley BruliD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 27 mutual co-author links

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3 shared papersMicrobiology

Benno H. ter KuileORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Driving factors for beta-lactam resistance gene amplification during de novo resistance evolution in E. coli

Luyuan Nong, Xinwei Liu, Xinyu Wang, Wim C. de Leeuw, Martijs J. Jonker, Stanley Brul, Benno H. ter Kuile

This study shows that ampC gene amplification drives beta-lactam resistance in E. coli, with resistance gene location affecting amplification targets but not the mechanism.

Antimicrobial Agents and Chemotherapy · Jul 23, 2025Peer-reviewedMicrobiology

Collateral sensitivity and cross resistance in six species of bacteria exposed to six classes of antibiotics

Xinyu Wang, Luyuan Nong, Gioia Schaar, Belinda B. Koenders, Martijs J. Jonker, Wim C. de Leeuw, Benno H. ter Kuile

The paper investigates collateral sensitivity and cross-resistance networks in six bacterial species after induced resistance to six antibiotics, finding specific patterns and genetic mechanisms.

Microbiology Spectrum · Jun 20, 2025Peer-reviewedMicrobiology

Progression of ampC amplification during de novo amoxicillin resistance development in E. coli

Luyuan Nong, Martijs J. Jonker, Wim C. de Leeuw, Meike T. Wortel, Benno H. ter Kuile

This study tracks ampC amplification and promoter mutations during de novo amoxicillin resistance development in E. coli, showing amplification occurs after promoter mutations and is facilitated by IS1 transposition.

mBio · Dec 20, 2024Peer-reviewedMicrobiology