Unveiling immune interference: How the dendritic cell response to co-infection with Aspergillus fumigatus is modulated by human cytomegalovirus and its virokine CMVIL-10
Linda Heilig, Lydia Bussemer, Lea Strobel, Kerstin Hünniger-Ast, Oliver Kurzai, Arnhild Grothey, Lars Dölken, Kerstin Laib Sampaio, Gianni Panagiotou, Alexander J. Westermann, Hermann Einsele, Sebastian Wurster, Sascha Schäuble, Jürgen Löffler
This study investigates how HCMV and its virokine CMVIL-10 modulate dendritic cell responses during co-infection with A. fumigatus, revealing that CMVIL-10 has a limited role in suppressing antifungal immunity.
bioRxiv · May 15, 2025 · PreprintImmunology