Author

Juergen Loeffler

Universitätsklinikum WürzburgORCID 0000-0001-6619-1100Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Gianni PanagiotouiD· 3 shared Hermann EinseleiD· 3 shared Sascha SchäubleiD· 3 shared Alexander J. WestermanniD· 2 shared Andreas BeilhackiD· 2 shared Dalia ShetaiD· 2 shared Kerstin Hünniger-Ast· 2 shared Oliver KurzaiiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersImmunology

Gianni PanagiotouORCID

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3 papers

Recent·Most cited

MicrobiologyFrontiers in MicrobiologyPeer-reviewedOct 8, 2026

Integrative phenotypic and transcriptomic validation of an alveolar-like macrophage model reveals early host-pathogen dynamics during Aspergillus fumigatus infection

Jeany Söhnlein, Sascha Schäuble, Juan Pablo Prada…·Juergen Loeffler

This study validates an alveolar-like macrophage model as a physiologically relevant in vitro system for studying early Aspergillus fumigatus infection dynamics.

DOI 10.3389/fmicb.2026.1922948

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintJul 9, 2026

M-CSF stimulated alveolar macrophages safeguard from invasive aspergillosis

Dalia Sheta, Zeinab Mokhtari, Marlene Strobel…·Andreas Beilhack

This study shows that M-CSF enhances alveolar macrophage function to protect against invasive aspergillosis in immunocompromised mice.

DOI 10.64898/2026.07.06.736478

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintMay 15, 2025

Unveiling immune interference: How the dendritic cell response to co-infection with Aspergillus fumigatus is modulated by human cytomegalovirus and its virokine CMVIL-10

Linda Heilig, Lydia Bussemer, Lea Strobel…·Jürgen Löffler

This study investigates how HCMV and its virokine CMVIL-10 modulate dendritic cell responses during co-infection with A. fumigatus, revealing that CMVIL-10 has a limited role in suppressing antifungal immunity.

DOI 10.1101/2025.05.15.654194

humanbulk RNA-seq

𝕏 PostBluesky