A small molecule probe elucidates the role of mitochondrial translocase TIMM44 in PINK1/Parkin regulated mitophagy
M. A. Conti, E. R. Torres, A. M. van der Bliek, C. Koehler
This study uses a small molecule probe to show that TIMM44 regulates PINK1 trafficking and mitophagy by affecting Parkin recruitment and mitochondrial quality control.
bioRxiv · Feb 16, 2022 · PreprintBiochemistry