M. A. Daniels

Anti-EGFR aptamer exhibits direct anti-cancer effects in NSCLC cells harboring EGFR L858R mutations

This study shows that an anti-EGFR aptamer reduces viability of NSCLC cells with EGFR L858R mutations and tumor burden in a mouse model, with cell line-dependent mechanisms.

STING controls T cell memory fitness during infection through T cell intrinsic and IDO dependent mechanisms

This study shows that STING signaling impairs T cell memory through intrinsic and IDO-dependent mechanisms, with TCR signal strength modulating this effect.

IKK2/NFkB signaling controls lung resident CD8 T cell memory during influenza infection

This study shows that NFkB signaling, controlled by IKK2, enhances lung CD8 TRM maintenance after influenza infection but impairs TRM differentiation during the contraction phase.

Lipidated poly(amino acid) nanostructures as versatile therapeutic delivery vehicles

The paper develops lipidated poly(amino acid) nanostructures for drug delivery, showing they can self-assemble and deliver doxorubicin to lymphoma cells.

Ramified Rolling Circle Amplification for efficient and flexible synthesis of nucleosomal DNA sequences

This paper introduces a method to efficiently synthesize nucleosomal DNA sequences using ramified rolling circle amplification, demonstrating its ability to produce functional nucleosomes from genomic DNA.