STING controls T cell memory fitness during infection through T cell intrinsic and IDO dependent mechanisms
E. Teixeiro, M. J. Quaney, R. J. Newth, K. M. Knudson, V. Saxena, C. J. Pritzl, C. S. Rae, P. Lauer, M. A. Daniels
This study shows that STING signaling impairs T cell memory through intrinsic and IDO-dependent mechanisms, with TCR signal strength modulating this effect.
bioRxiv · Mar 19, 2022 · PreprintImmunology