Author

M. A. Grotzer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1

Frequent Co-Authors

M. Baumgartner· 3 shared A. Gries· 2 shared C. Capdeville· 2 shared J. Migliavacca· 2 shared B. Zuellig· 1 shared D. Penton· 1 shared F. Kuttler· 1 shared K. Santhana Kumar· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCancer Biology

M. Baumgartner

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Author profile →

3 papers

Recent·Most cited

Repression of Aurora kinase B prevents growth and tissue invasion in medulloblastoma

A. Gries, K. Santhana Kumar, F. Kuttler, M. A. Grotzer, M. Baumgartner

This study identifies AURKB as a therapeutic target in medulloblastoma, showing that its inhibition in the tissue context effectively restricts tumor growth and invasiveness, comparable to irradiation.

bioRxiv · Jun 23, 2023 · PreprintCancer Biology

CD155 and EndoA1 mediate growth and tissue invasion downstream of MAP4K4 in medulloblastoma cells

C. Capdeville, L. Russo, D. Penton, J. Migliavacca, M. Zecevic, A. Gries, S. C. F. Neuhauss, M. A. Grotzer, M. Baumgartner

This study identifies CD155 and EndoA1 as downstream effectors of MAP4K4 that regulate medulloblastoma cell growth and tissue invasion through changes in the plasma membrane proteome.

bioRxiv · Aug 10, 2021 · PreprintCell Biology

Striatin 3 and MAP4K4 cooperate towards oncogenic growth and tissue invasion in medulloblastoma

J. Migliavacca, B. Zuellig, C. Capdeville, M. A. Grotzer, M. Baumgartner

This study identifies STRN3 and MAP4K4 as cooperating factors that promote medulloblastoma growth and invasion by modulating Hippo signaling and PKCθ/VASP pathways.

bioRxiv · May 7, 2021 · PreprintCancer Biology